Argegno (Comasco: Argegn) is a comune (municipality) in the Province of Como in the Italian region Lombardy, located about 50 kilometres (31 mi) north of Milan and about 15 kilometres (9 mi) north of Como. As of March 2024, it had a population of 679 and an area of 4.3 square kilometres (1.7 sq mi).

The local economy is heavily dependent upon tourism and the service industry. the official tourist website for Argegno is www.visitargegno.com.

A cable car can transport people up to the nearby village of Pigra.

Argegno is situated on an inlet in the lake, and is built alongside the River Telo which flows into the lake, the discharge of which is heavily dependent upon the season.