Osmate was a comune (municipality) in the Province of Varese in the Italian region Lombardy , located about 50 kilometres (31 mi) northwest of Milan and about 13 kilometres (8 mi) southwest of Varese. As of 31 December 2004, it had a population of 550 and an area of 3.4 square kilometres (1.3 sq mi).

In 2019 it merged with the nearby Cadrezzate forming the new municipality of Cadrezzate con Osmate.