Guebwiller (French pronunciation: [ɡebvilɛʁ] ; Alsatian: Gàwiller [ˈkaːviləʁ]; German: Gebweiler) is a commune in the Haut-Rhin département in Grand Est in north-eastern France. It was a sub-prefecture of the department until 2015.

It is situated 20 km (12 mi) northwest of Mulhouse at the foot of the Vosges mountains. The Ballon de Guebwiller, the highest point in the Vosges, lies 8 km (5.0 mi) to the west of the town.

In 2018, Guebwiller had a population of 11,022 and its urban area had a population of 28,662.

Guebweiler, as Gebweiler, is mentioned as early as 774.