Novate Mezzola is a comune (municipality) in the Province of Sondrio in the Italian region Lombardy , located about 90 kilometres (56 mi) north of Milan and about 35 kilometres (22 mi) west of Sondrio, on the border with Switzerland. As of 31 December 2004, it had a population of 1,713 and an area of 99.7 square kilometres (38.5 sq mi).

Novate Mezzola borders the following municipalities: Bondo (Switzerland), Cercino , Cino , Civo , Dubino , Mello, Piuro , Prata Camportaccio , Samolaco , Sorico , Traona , Val Masino , Verceia , Villa di Chiavenna .