Wolhusen is a municipality in the district of Entlebuch in the Canton of Lucerne in Switzerland .

Wolhusen has an area of 14.3 km2 (5.5 sq mi). Of this area, 58.1% is used for agricultural purposes, while 32.6% is forested. Of the rest of the land, 8.6% is settled (buildings or roads) and the remainder (0.7%) is non-productive (rivers, glaciers or mountains). In the 1997 land survey, 32.61% of the total land area was forested. Of the agricultural land, 54.51% is used for farming or pastures, while 3.5% is used for orchards or vine crops.