The Munich–Garmisch-Partenkirchen railway is a single track, electrified main line railway in the southern part of the German state of Bavaria. It runs from Munich via Starnberg and Murnau to Garmisch-Partenkirchen. The first part of it was opened in 1854 and is one of the oldest lines in Germany.

On 3 June 2022 in the Burgrain train derailment , a regional train derailed on a single track curve at Burgrain, north of Garmisch-Partenkirchen station .

The line runs for 7.4 km from the Starnberg wing of Munich Hauptbahnhof to Munich-Pasing station. The route to Tutzing runs parallel to S-Bahn line S6.