Lake Iseo or Iseo lake (US: ee-ZAY-oh; Italian: Lago d'Iseo Italian pronunciation: [ˈlaːɡo diˈzɛːo]; Eastern Lombard: Lach d'Izé), also known as Sebino (Italian: [seˈbiːno]; Latin: Sebinus), is the fourth largest lake in Lombardy , Italy, fed by the Oglio River.

It is in the north of the country in the Val Camonica area, near the cities of Brescia and Bergamo . The lake is almost equally divided between the provinces of Bergamo and Brescia. Northern Italy is known for its heavily industrialised towns and in between there are several natural lakes. Lake Iseo retains its natural environment, with its lush green mountains surrounding the crystal clear lake.

There are several medieval towns around the lake, the largest being Iseo and Sarnico .