Scopello is a comune (municipality) located in the Valsesia region of the Italian Pennine Alps , administratively in the Province of Vercelli , Piedmont . The municipality covers an area of 18.62 square kilometres (7.19 sq mi) and ranges in elevation from 640 to 1,930 metres (2,100 to 6,330 ft) above sea level. It takes its name from its main centre, the small town of Scopello, which stands on the river Sesia at an elevation of 659 metres (2,162 ft).

Other centres include Casa Pareti, Chioso, Frasso, Villabella, and Alpe di Mera. The latter, as the name Alpe suggests, once provided summer pasture for livestock, and today is a winter ski resort.

Scopello borders Boccioleto , Campertogno , Caprile , Crevacuore , Guardabosone , Pettinengo , Pila, Piode , Scopa, Trivero, and Valle San Nicolao.