The Simplon Hospice is a large building where travellers and merchants can get food, accommodation and shelter from the harsh climate. In a decree of 21 February 1801 Napoleon Bonaparte commissioned the building of a hospice on top of the Simplon Pass . The hospice has always been run by the Canons of Saint Augustine.

The Simplon Hospice is located 1,998 m (6,555 ft) above sea level at the mountain saddle of the Simplon Pass.

The Napoleon-Road over the Simplon Pass and through the Gorge of Gondo was opened in 1806.