Calasca-Castiglione is a comune (municipality) in the Province of Verbano-Cusio-Ossola in the Italian region Piedmont , located about 120 kilometres (75 mi) northeast of Turin and about 35 kilometres (22 mi) northwest of Verbania .

Calasca-Castiglione borders the following municipalities: Antrona Schieranco , Bannio Anzino , Borgomezzavalle , Pallanzeno , Piedimulera , Pieve Vergonte , Rimella , Valstrona , Vanzone con San Carlo .