Antrona Schieranco is a comune (municipality) in the Province of Verbano-Cusio-Ossola in the Italian region Piedmont, located about 120 kilometres (75 mi) northeast of Turin and about 35 kilometres (22 mi) northwest of Verbania, in the Valle Antrona, a branch of the Val d'Ossola, on the border with Switzerland.

Antrona Schieranco borders the following municipalities: Bognanco, Borgomezzavalle, Calasca-Castiglione, Ceppo Morelli, Montescheno, Saas Almagell (Switzerland), Vanzone con San Carlo, Zwischbergen (Switzerland). Until 1946, it was a center for silver and gold mining.

The Portjengrat (Italian: Pizzo d'Andolla) is located nearby.