The Gotthard Pass or St. Gotthard Pass (Italian: Passo del San Gottardo; German: Gotthardpass) at 2,106 m (6,909 ft) is a mountain pass in the Alps traversing the Saint-Gotthard Massif and connecting northern Switzerland with southern Switzerland. The pass lies between Airolo in the Italian-speaking canton of Ticino , and Andermatt in the German-speaking Canton of Uri , and connects further Bellinzona and Lugano to Lucerne , Basel , and Zürich. The Gotthard Pass lies at the heart of the Gotthard, a major transport axis of Europe, and it is crossed by three traffic tunnels, each being the world's longest at the time of their construction: the Gotthard Rail Tunnel (1882), the Gotthard Road Tunnel (1980) and the Gotthard Base Tunnel (2016). With the Lötschberg to the west, the Gotthard is one of the two main north-south routes through the Swiss Alps .

Since the Middle Ages, transit across the Gotthard played an important role in Swiss history, the region north of the Gotthard becoming the nucleus of the Swiss Confederacy in the 13th century, after the pass became a vital trade route between Northern and Southern Europe.