Col des Mosses (elevation 1445 m) is a mountain pass in the western Bernese Alps of Switzerland. The pass is located in the municipality of Ormont-Dessous in the canton of Vaud. It links Aigle, to the south in the valley of the Rhone, with Château-d'Œx, to the north in the valley of the Sarine, and is flanked to the west by the Mont d'Or and to the east by the Pic Chaussy.

The pass is traversed by a major road between Aigle and Château-d'Œx. From Aigle, the road ascends 1,028 metres (3,373 ft) over a distance of 18.8 kilometres (11.7 mi), whilst from Château-d'Œx it ascends 521 metres (1,709 ft) over 14 kilometres (8.7 mi). The road is normally kept open throughout the year.