Marcallo con Casone (Milanese: Marcall cont el Cason [marˈkal kũt el kaˈzũː]) is a comune (municipality) in the Metropolitan City of Milan in the Italian region Lombardy, located about 20 kilometres (12 mi) west of Milan.

Marcallo con Casone borders the following municipalities: Ossona, Mesero, Santo Stefano Ticino, Bernate Ticino, Magenta, Boffalora sopra Ticino.