Montemezzo (Comasco: Montemezz [mũteˈmɛts]) is a comune (municipality) in the Province of Como in the Italian region Lombardy, located about 80 kilometres (50 mi) north of Milan and about 45 kilometres (28 mi) northeast of Como. As of 31 December 2004, it had a population of 270 and an area of 9.1 km2.

Montemezzo borders the following municipalities: Gera Lario, Samolaco, Sorico, Trezzone, Vercana.