The Mincio (Italian: [ˈmintʃo]; Lombard: Mens; Venetian: Menzo; Latin: Mincius; Ancient Greek: Μίγχιος, romanized: Mínchios) is a river in the Lombardy region of northern Italy.

The river is the main outlet of Lake Garda. It is a part of the Sarca-Mincio river system which also includes the river Sarca and the Lake Garda. The river starts from the south-eastern tip of the lake at the town of Peschiera del Garda and then flows for about 65 kilometres (40 mi) past Mantua and into the river Po. From Lake Garda until it reaches Pozzolo, it forms the boundary between Veneto and Lombardy regions.

In the Etruscan period, the Mincio probably joined with the river Tartaro and flowed into the Adriatic Sea into the pit Filistina, in Roman Republic it was made to flow into the Po with three branches from Mantua by Quintus Curius Hostilius, subsequently reunited in a single embanked in 1198 on a project by Alberto Pitentino and regulated its course with several dams (Ponte dei Mulini, Mantua) and the Governolo) dam to make it navigable, to prevent Mantua from being flooded by the flooding of the Po and to improve air quality.