Pagnona (Valvarronese: Pagnone) is a comune (municipality) in the Province of Lecco in the Italian region Lombardy, located about 70 kilometres (43 mi) northeast of Milan and about 25 kilometres (16 mi) north of Lecco.

Pagnona borders the following municipalities: Casargo, Colico, Delebio, Piantedo, Premana, Tremenico.